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Gadopentetic acid

Name: Gadopentetic acid
Brand: TargetMol
SKU: T19332
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19332Cas No. 80529-93-7

Alias Gd-DTPA, gadolinium complex

Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.

Gadopentetic acid

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Catalog No. T19332Alias Gd-DTPA, gadolinium complexCas No. 80529-93-7

Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.

Pack Size	Price	Availability	Quantity
100 mg	$41	In Stock

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Product Introduction

Bioactivity

Description	Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.
In vivo	The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI.?[Gd-DTPA0] is related to the administered bolus dose and varies with subjects.?A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L.
Alias	Gd-DTPA, gadolinium complex

Chemical Properties

Molecular Weight	547.57
Formula	C₁₄H₂₀GdN₃O₁₀
Cas No.	80529-93-7
Smiles	O=C1[O-][Gd+3]23([O-]C4=O)([O-]C5=O)([O-]C6=O)([N](CC[N]3(C5)C6)(C1)CC[N]2(C7)C4)[O-]C7=O.[H+].[H+]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 100 mg/mL (182.63 mM), Sonication is recommended.

DMSO: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8263 mL	9.1313 mL	18.2625 mL	91.3125 mL
5 mM	0.3653 mL	1.8263 mL	3.6525 mL	18.2625 mL
10 mM	0.1826 mL	0.9131 mL	1.8263 mL	9.1313 mL
20 mM	0.0913 mL	0.4566 mL	0.9131 mL	4.5656 mL
50 mM	0.0365 mL	0.1826 mL	0.3653 mL	1.8263 mL
100 mM	0.0183 mL	0.0913 mL	0.1826 mL	0.9131 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

paramagnetic contrastnephrogenic systemic fibrosis (NSF)intravenous injectionInhibitorinhibitGadopentetic acid