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GDC-0834 S-enantiomer

Name: GDC-0834 S-enantiomer
Brand: TargetMol
SKU: T11378
Rating: 4.5 (1 reviews)

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Catalog No. T11378Cas No. 1133432-50-4

GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).

GDC-0834 S-enantiomer

😃Good

Catalog No. T11378Cas No. 1133432-50-4

GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).

Pack Size	Price	Availability
25 mg	$985	6-8 weeks
50 mg	$1,280	6-8 weeks
100 mg	$1,940	6-8 weeks

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Product Introduction

Bioactivity

Description

GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).

Chemical Properties

Molecular Weight	596.74
Formula	C₃₃H₃₆N₆O₃S
Cas No.	1133432-50-4
Relative Density.	1.35 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (167.58 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6758 mL	8.3789 mL	16.7577 mL	83.7886 mL
5 mM	0.3352 mL	1.6758 mL	3.3515 mL	16.7577 mL
10 mM	0.1676 mL	0.8379 mL	1.6758 mL	8.3789 mL
20 mM	0.0838 mL	0.4189 mL	0.8379 mL	4.1894 mL
50 mM	0.0335 mL	0.1676 mL	0.3352 mL	1.6758 mL
100 mM	0.0168 mL	0.0838 mL	0.1676 mL	0.8379 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

GDC 0834 S enantiomerGDC0834 SenantiomerGDC-0834 S-enantiomer