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Glufosinate ammonium
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Catalog No. T15391Cas No. 77182-82-2
Glufosinate ammonium is a phosphinic acid analogue of glutamic acid and is an herbicide. Glufosinate ammonium is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium has neurotoxic activity.
Glufosinate ammonium
🥰Excellent
Purity: 100%
Catalog No. T15391Cas No. 77182-82-2
Glufosinate ammonium is a phosphinic acid analogue of glutamic acid and is an herbicide. Glufosinate ammonium is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium has neurotoxic activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $66 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Glufosinate ammonium is a phosphinic acid analog of glutamic acid and an herbicide with neurotoxic activity. It is converted by plant cells into PT (L-phosphinothricin). |
| In vitro | Glufosinate ammonium impairs ependymal cell capability to synthetize cilia. Glufosinate ammonium (1-100 μM; 12DIV) obviously reduces Celsr2 gene expression at 100 μM. Glufosinate ammonium (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs) [2]. |
| In vivo | Glufosinate ammonium (10-250 mg/kg; gavage; daily; on days 6-15 of gestation) exhibits maternal toxicity at doses of 50 or 250 mg/kg in Wistar rats. In both male and female rats, the elimination of Glufosinate ammonium (oral intubation) from the blood has a half-life of less than 4 hours [3]. |
| Molecular Weight | 198.16 |
| Formula | C5H15N2O4P |
| Cas No. | 77182-82-2 |
| Smiles | CP(O)(CCC(C([O-])=O)N)=O.[NH4+] |
| Relative Density. | 1.4 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 250 mg/mL (1261.61 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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