Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GLUT inhibitor-1 is an orally active GLUT inhibitor with IC50 s of 242 nM and 179 nM for GLUT1 and GLUT3. GLUT inhibitor-1 can be used in studies about cancers and autoimmune diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 648.00 | |
10 mg | Inquiry | $ 997.00 | |
25 mg | Inquiry | $ 1,990.00 | |
100 mg | Inquiry | Inquiry |
Description | GLUT inhibitor-1 is an orally active GLUT inhibitor with IC50 s of 242 nM and 179 nM for GLUT1 and GLUT3. GLUT inhibitor-1 can be used in studies about cancers and autoimmune diseases. |
Targets&IC50 | GLUT3:179 nM (IC50), GLUT1:242 nM (IC50) |
In vivo | GLUT inhibitor-1 exhibits good oral pharmacokinetic parameters in mice and rats with oral Cmax values of 2525 and 1675 ng/mL, AUCs of 5890 and 6813 ng/mL, CLs of 40 and 37 mL/min/kg, Vdss of 1.70 and 4.51 L/Kg, t1/2s of 0.785 and 2.59h and Fs of 45.4% and 49.4%[1]. |
Molecular Weight | 549.67 |
Formula | C32H35N7O2 |
CAS No. | 2421141-40-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (163.7 mM), Sonification and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GLUT inhibitor-1 2421141-40-2 Metabolism transporter GLUT inhibitor1 GLUT inhibitor 1 inhibitor inhibit