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Glycolithocholic acid 3-sulfate

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Catalog No. T73758Cas No. 15324-64-8
Alias Sulfolithocholylglycine, SLCG, Glycolithocholate sulfate

Glycolithocholic acid 3-sulfate (SLCG) is a bile acid derivative and metabolite of glycocholic acid, selectively inhibiting HIV-1 replication in vitro, used in the study of HIV infection.

Glycolithocholic acid 3-sulfate

Glycolithocholic acid 3-sulfate

🥰Excellent
Purity: 99%
Catalog No. T73758Alias Sulfolithocholylglycine, SLCG, Glycolithocholate sulfateCas No. 15324-64-8
Glycolithocholic acid 3-sulfate (SLCG) is a bile acid derivative and metabolite of glycocholic acid, selectively inhibiting HIV-1 replication in vitro, used in the study of HIV infection.
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1 mg$159In Stock
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Purity:99%
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Product Introduction

Bioactivity
Description
Glycolithocholic acid 3-sulfate (SLCG) is a bile acid derivative and metabolite of glycocholic acid, selectively inhibiting HIV-1 replication in vitro, used in the study of HIV infection.
In vitro
Glycolithocholic acid 3-sulfate (100 μg/ml) fully protected MT-4 cells from HIV-1-induced cellular pathogenicity, while no toxicity to host cells was observed at concentrations of 200 μg/ml. Glycolithocholic acid 3-sulfate inhibited the expression of HIV-1 antigen in HIV-1-infected CEM cells. [1]
AliasSulfolithocholylglycine, SLCG, Glycolithocholate sulfate
Chemical Properties
Molecular Weight513.69
FormulaC26H43NO7S
Cas No.15324-64-8
SmilesC[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](OS(=O)(=O)O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H]
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3 mg/mL (5.84 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9467 mL9.7335 mL19.4670 mL97.3350 mL
5 mM0.3893 mL1.9467 mL3.8934 mL19.4670 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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