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KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 μM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $73 | In Stock | |
10 mg | $116 | In Stock | |
25 mg | $248 | In Stock | |
50 mg | $369 | In Stock | |
100 mg | $526 | In Stock | |
200 mg | $723 | In Stock | |
1 mL x 10 mM (in DMSO) | $80 | In Stock |
Description | KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 μM. |
Targets&IC50 | Proliferation (T-cells):~5 μM |
Molecular Weight | 252.33 |
Formula | C15H12N2S |
Cas No. | 79220-94-3 |
Smiles | S=c1[nH]c(cn1-c1ccccc1)-c1ccccc1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 25.23 mg/mL (100 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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