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Lanoconazole
🥰Excellent
Catalog No. T15708Cas No. 101530-10-3
Alias TJN318, NND-318, NND318, M-110101, M-1100, M1100
Lanoconazole is an antifungal imidazole drug used primarily for the treatment of fungal skin infections that is potent and orally available. It acts by inhibiting the synthesis of ergosterol in fungal cell membranes, increasing the permeability of fungal cell membranes, leading to cell lysis and death. Lanoconazole exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., and Candida spp..
Lanoconazole
🥰Excellent
Purity: 98%
Catalog No. T15708Alias TJN318, NND-318, NND318, M-110101, M-1100, M1100Cas No. 101530-10-3
Lanoconazole is an antifungal imidazole drug used primarily for the treatment of fungal skin infections that is potent and orally available. It acts by inhibiting the synthesis of ergosterol in fungal cell membranes, increasing the permeability of fungal cell membranes, leading to cell lysis and death. Lanoconazole exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., and Candida spp..
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $49 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Lanoconazole is an antifungal imidazole drug used primarily for the treatment of fungal skin infections that is potent and orally available. It acts by inhibiting the synthesis of ergosterol in fungal cell membranes, increasing the permeability of fungal cell membranes, leading to cell lysis and death. Lanoconazole exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., and Candida spp.. |
| In vivo | Lanoconazole (3, 10, or 30 mg/kg, orally, once daily for 3 weeks) significantly reduces the growth of C. neoformans in the lungs and brain of mice.[3] |
| Alias | TJN318, NND-318, NND318, M-110101, M-1100, M1100 |
| Molecular Weight | 319.83 |
| Formula | C14H10ClN3S2 |
| Cas No. | 101530-10-3 |
| Smiles | C(\C#N)(=C/1\SC(CS1)C2=C(Cl)C=CC=C2)/N3C=CN=C3 |
| Relative Density. | 1.43 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (250.13 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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