Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production of LTB4 by human polymorphonuclear leukocytes and displays relatively weak inhibition on cycloox |
In vitro | LY178002 suppresses the generation of LTB4, PLA2 and FCO (IC50s of 0.1, 6.3 and 4.2 μM) . |
In vivo | LY 178002 (50 mg/kg) inhibits soft tissue swelling in the uninjected paw by 81% and inhibits bone damage in rats. LY178002 (50 mg/kg; p.o.) inhibits the uninjected paw swelling by 75%, in the established FCA model. The minimum effective dose for LY178002 is 10 mg/kg p.o. |
Molecular Weight | 319.46 |
Formula | C18H25NO2S |
Cas No. | 107889-32-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.