Shopping Cart

Remove All

Your shopping cart is currently empty

ML328

Select Batch

Resource Download

COA HNMR

ML328

Catalog No. T9678Cas No. 634175-34-1

ML328 is a potent and selective inhibitor of bacterial AddAB(IC50 = 1.0 μM) and RecBCD(IC50 = 4.8 μM) helicase-nucleases.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$60	In Stock
5 mg	$147	In Stock
10 mg	$239	In Stock
25 mg	$455	In Stock
50 mg	$665	In Stock
100 mg	$928	In Stock
1 mL x 10 mM (in DMSO)	$193	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "ML328"

Product Introduction

Bioactivity

Description	ML328 is a potent and selective inhibitor of bacterial AddAB(IC50 = 1.0 μM) and RecBCD(IC50 = 4.8 μM) helicase-nucleases.
Targets&IC50	AddAB:1.0 μM, RecBCD:4.8 μM
In vitro	The probe ML328 has a half-life of over 48 hours in PBS at room temperature when tested at 10 μM. Disappearance of the LC peak for the probe is unaltered by the addition of excess glutathione (50 μM) in a 6 hour incubation[1].

Chemical Properties

Molecular Weight	506.5
Formula	C22H21F3N6O3S
Cas No.	634175-34-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (98.72 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9743 mL	9.8717 mL	19.7433 mL	98.7167 mL
5 mM	0.3949 mL	1.9743 mL	3.9487 mL	19.7433 mL
10 mM	0.1974 mL	0.9872 mL	1.9743 mL	9.8717 mL
20 mM	0.0987 mL	0.4936 mL	0.9872 mL	4.9358 mL
50 mM	0.0395 mL	0.1974 mL	0.3949 mL	1.9743 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ML-328ML 328ML328