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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | Inquiry | Backorder | |
100 mg | Inquiry | Backorder |
Description | MS645 is an inhibitor of bromodomain-containing protein 4 (BRD4) with a Ki of 18.4 nM for BRD4-BD1/BD2. |
In vitro | MS645 blocks the proliferation of triple-negative breast cancer (TNBC) cells. MS645 down-regulates proinflammatory cytokines and genes for cell-cycle control and DNA damage repair that are largely unaffected by monovalent BRD inhibition[1]. |
Molecular Weight | 938.04 |
Formula | C48H54Cl2N10O2S2 |
Cas No. | 2250091-96-2 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 180 mg/mL (191.9 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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