All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Myrcene is a terpene that has been found in Cannabis and has antioxidative properties.
In vivo	Myrcene showed antioxidant activity and eliminated TCDD-induced oxidative stress in rats in a time-dependent manner.
Animal Research	Rats (n = 112) were divided randomly into 8 equal groups. One group was kept as control and given corn oil as carrier. TCDD was orally administered at the dose of 2 μg/kg/week. Curcumin, myrcene and cineole were orally administered at the doses of 100 mg/kg/day, 200 mg/kg/day and 100 mg/kg/ day, respectively, by gavages dissolved in corn oil with and without TCDD. The liver samples were taken from half of all rats on day 30 and from the remaining half on day 60 for the determination of thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH), catalase (CAT), glutathione peroxidase (GSH-Px) and CuZn-SOD levels by spectrophotometric method. The results indicated that although TCDD significantly (p ≤ 0.01) increased formation of TBARS, it caused a significant decline in the levels of GSH, CAT, GSH-Px and CuZn-SOD in rats.

Chemical Properties

Molecular Weight	136.23
Formula	C₁₀H₁₆
Cas No.	123-35-3
Smiles	CC(C)=CCCC(=C)C=C
Relative Density.	0.791 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (403.71 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.3405 mL	36.7026 mL	73.4053 mL	367.0264 mL
5 mM	1.4681 mL	7.3405 mL	14.6811 mL	73.4053 mL
10 mM	0.7341 mL	3.6703 mL	7.3405 mL	36.7026 mL
20 mM	0.3670 mL	1.8351 mL	3.6703 mL	18.3513 mL
50 mM	0.1468 mL	0.7341 mL	1.4681 mL	7.3405 mL
100 mM	0.0734 mL	0.3670 mL	0.7341 mL	3.6703 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

β-MyrceneTNFαNuclear factor-κBNuclear factor-kappaBNF-κBMyrceneInhibitorinhibitaromatic volatileanti-invasive effect