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N3-C2-NHS ester

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Catalog No. T18465Cas No. 850180-76-6
Alias 3-Azidopropanoic acid NHS ester

N3-C2-NHS ester (3-Azidopropanoic acid NHS ester) is an ADC linker, which is a cross-linking agent for macromolecular compounds, and can be used for the synthesis of antibody-coupled reactive molecules (ADCs).

N3-C2-NHS ester

N3-C2-NHS ester

🥰Excellent
Catalog No. T18465Alias 3-Azidopropanoic acid NHS esterCas No. 850180-76-6
N3-C2-NHS ester (3-Azidopropanoic acid NHS ester) is an ADC linker, which is a cross-linking agent for macromolecular compounds, and can be used for the synthesis of antibody-coupled reactive molecules (ADCs).
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5 mg$32In Stock
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Product Introduction

Bioactivity
Description
N3-C2-NHS ester (3-Azidopropanoic acid NHS ester) is an ADC linker, which is a cross-linking agent for macromolecular compounds, and can be used for the synthesis of antibody-coupled reactive molecules (ADCs).
Alias3-Azidopropanoic acid NHS ester
Chemical Properties
Molecular Weight212.16
FormulaC7H8N4O4
Cas No.850180-76-6
Smiles[N-]=[N+]=NCCC(=O)ON1C(=O)CCC1=O
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80.00 mg/mL (377.07 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.7134 mL23.5671 mL47.1342 mL235.6712 mL
5 mM0.9427 mL4.7134 mL9.4268 mL47.1342 mL
10 mM0.4713 mL2.3567 mL4.7134 mL23.5671 mL
20 mM0.2357 mL1.1784 mL2.3567 mL11.7836 mL
50 mM0.0943 mL0.4713 mL0.9427 mL4.7134 mL
100 mM0.0471 mL0.2357 mL0.4713 mL2.3567 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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