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N3-PEG4-C2-NHS ester

Catalog No. T16259Cas No. 944251-24-5

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

N3-PEG4-C2-NHS ester

N3-PEG4-C2-NHS ester

Purity: 99.85%
Catalog No. T16259Cas No. 944251-24-5
N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).
Pack SizePriceAvailabilityQuantity
10 mg$35In Stock
25 mg$54In Stock
50 mg$89In Stock
100 mg$129In Stock
500 mg$316In Stock
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Purity:99.85%
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Product Introduction

Bioactivity
Description
N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).
Chemical Properties
Molecular Weight388.37
FormulaC15H24N4O8
Cas No.944251-24-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (205.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5749 mL12.8743 mL25.7486 mL128.7432 mL
5 mM0.5150 mL2.5749 mL5.1497 mL25.7486 mL
10 mM0.2575 mL1.2874 mL2.5749 mL12.8743 mL
20 mM0.1287 mL0.6437 mL1.2874 mL6.4372 mL
50 mM0.0515 mL0.2575 mL0.5150 mL2.5749 mL
100 mM0.0257 mL0.1287 mL0.2575 mL1.2874 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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