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N3-Ph-NHS ester

Name: N3-Ph-NHS ester
Brand: TargetMol
SKU: T18476
Price: 27 EUR
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18476Cas No. 53053-08-0

N3-Ph-NHS ester is a noncleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs).

N3-Ph-NHS ester

🥰Excellent

Purity: 99.35%

Catalog No. T18476Cas No. 53053-08-0

N3-Ph-NHS ester is a noncleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Pack Size	Price	Availability
25 mg	27 €	In Stock
50 mg	37 €	In Stock
100 mg	54 €	In Stock

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Purity:99.35%

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COA HPLC HNMR

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Product Introduction

Bioactivity

Description

N3-Ph-NHS ester is a noncleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Chemical Properties

Molecular Weight	260.21
Formula	C₁₁H₈N₄O₄
Cas No.	53053-08-0
Smiles	[N-]=[N+]=Nc1ccc(cc1)C(=O)ON1C(=O)CCC1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 30 mg/mL (115.29 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8430 mL	19.2152 mL	38.4305 mL	192.1525 mL
5 mM	0.7686 mL	3.8430 mL	7.6861 mL	38.4305 mL
10 mM	0.3843 mL	1.9215 mL	3.8430 mL	19.2152 mL
20 mM	0.1922 mL	0.9608 mL	1.9215 mL	9.6076 mL
50 mM	0.0769 mL	0.3843 mL	0.7686 mL	3.8430 mL
100 mM	0.0384 mL	0.1922 mL	0.3843 mL	1.9215 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc