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Nauclefine (Parvine) is a plant indole alkaloid natural product and induces apoptosis of diverse cancer cells via a PDE3A-SLFN12 dependent death pathway. Nauclefine binds PDE3A but does not inhibit the PDE3A's phosphodiesterase activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 112 € | In Stock | |
2 mg | 169 € | In Stock | |
5 mg | 254 € | In Stock | |
10 mg | 375 € | In Stock | |
25 mg | Inquiry | In Stock | |
50 mg | Inquiry | In Stock |
Description | Nauclefine (Parvine) is a plant indole alkaloid natural product and induces apoptosis of diverse cancer cells via a PDE3A-SLFN12 dependent death pathway. Nauclefine binds PDE3A but does not inhibit the PDE3A's phosphodiesterase activity. |
In vivo | Nauclefine inhibits tumor xenograft growth in vivo, doing so in a PDE3A- and SLFN12-dependent manner[1]. |
Alias | Parvine |
Molecular Weight | 287.32 |
Formula | C18H13N3O |
Cas No. | 57103-51-2 |
Smiles | O=C1N2C(C3=C(C=4C(N3)=CC=CC4)CC2)=CC=5C1=CN=CC5 |
Relative Density. | 1.46g/cm3 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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