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Neostigmine bromide

🥰Excellent
Catalog No. T1624Cas No. 114-80-7
Alias Neoserine bromide, Eustigmin bromide

Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.

Neostigmine bromide

Neostigmine bromide

🥰Excellent
Purity: 98.02%
Catalog No. T1624Alias Neoserine bromide, Eustigmin bromideCas No. 114-80-7
Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
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Purity:98.02%
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Product Introduction

Bioactivity
Description
Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
AliasNeoserine bromide, Eustigmin bromide
Chemical Properties
Molecular Weight303.2
FormulaC12H19BrN2O2
Cas No.114-80-7
Smiles[Br-].CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
Relative Density.1.4344 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 38 mg/mL (125.33 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2982 mL16.4908 mL32.9815 mL164.9077 mL
5 mM0.6596 mL3.2982 mL6.5963 mL32.9815 mL
10 mM0.3298 mL1.6491 mL3.2982 mL16.4908 mL
20 mM0.1649 mL0.8245 mL1.6491 mL8.2454 mL
50 mM0.0660 mL0.3298 mL0.6596 mL3.2982 mL
100 mM0.0330 mL0.1649 mL0.3298 mL1.6491 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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