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NHS-C4-MTS

NHS-C4-MTS
N-Succinimidyloxycarbonylpropyl methanethiosulfonate (SMPM) is a non-cleavable antibody-drug conjugate (ADC) linker employed for ADC synthesis[1].
Catalog No. T18463Cas No. 690632-55-4
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NHS-C4-MTS

Catalog No. T18463Cas No. 690632-55-4
N-Succinimidyloxycarbonylpropyl methanethiosulfonate (SMPM) is a non-cleavable antibody-drug conjugate (ADC) linker employed for ADC synthesis[1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
N-Succinimidyloxycarbonylpropyl methanethiosulfonate (SMPM) is a non-cleavable antibody-drug conjugate (ADC) linker employed for ADC synthesis[1].
In vitro
ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker[1].
AliasN-Succinimidyloxycarbonylpropyl methanethiosulfonate
Chemical Properties
Molecular Weight295.33
FormulaC9H13NO6S2
Cas No.690632-55-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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