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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
2 mg | $136 | In Stock | |
5 mg | $198 | In Stock | |
10 mg | $298 | In Stock | |
25 mg | $475 | In Stock | |
50 mg | $678 | In Stock | |
100 mg | $912 | In Stock | |
500 mg | $1,780 | In Stock | |
1 mL x 10 mM (in DMSO) | $229 | In Stock |
Description | NMS-859 is an effective and covalent inhibitor of valosin-containing protein (VCP)/p97 with IC50s of 0.37 μM and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. |
In vitro | NMS-859 suppresses the cell proliferation with IC50s of 3.0 μM and 3.5 μM in HeLa and HCT116 cell lines, respectively. NMS-859 shows weak inhibitory activity against VCPC522T[1]. |
Alias | ZINC169324353 |
Molecular Weight | 349.79 |
Formula | C15H12ClN3O3S |
Cas No. | 1449236-96-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | DMSO: 3.5 mg/mL (10 mM) ![]() | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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