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NPAS3-IN-1

🥰Excellent
Catalog No. T81646Cas No. 2207-44-5

NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, modulating NPAS3 transcription by targeting the interaction between NPAS3 and ARNT at the cellular level.

NPAS3-IN-1

NPAS3-IN-1

🥰Excellent
Purity: 99.56%
Catalog No. T81646Cas No. 2207-44-5
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, modulating NPAS3 transcription by targeting the interaction between NPAS3 and ARNT at the cellular level.
Pack SizePriceAvailabilityQuantity
1 mg$76In Stock
5 mg$188In Stock
10 mg$297In Stock
25 mg$519In Stock
50 mg$738In Stock
100 mg$987In Stock
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Purity:99.56%
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Product Introduction

Bioactivity
Description
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, modulating NPAS3 transcription by targeting the interaction between NPAS3 and ARNT at the cellular level.
Chemical Properties
Molecular Weight295.36
FormulaC10H5N3O2S3
Cas No.2207-44-5
SmilesO=[N+]([O-])C1=CN=C(SC2=NC3=C(S2)C=CC=C3)S1
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (67.71 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3857 mL16.9285 mL33.8570 mL169.2849 mL
5 mM0.6771 mL3.3857 mL6.7714 mL33.8570 mL
10 mM0.3386 mL1.6928 mL3.3857 mL16.9285 mL
20 mM0.1693 mL0.8464 mL1.6928 mL8.4642 mL
50 mM0.0677 mL0.3386 mL0.6771 mL3.3857 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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