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NPB

🥰Excellent
Catalog No. T12249Cas No. 2247491-97-8
Alias Alpha-NPB

NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)

NPB

NPB

🥰Excellent
Purity: 100%
Catalog No. T12249Alias Alpha-NPBCas No. 2247491-97-8
NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)
Pack SizePriceAvailabilityQuantity
1 mg$73In Stock
5 mg$179In Stock
10 mg$297In Stock
25 mg$488In Stock
50 mg$679In Stock
100 mg$893In Stock
1 mL x 10 mM (in DMSO)$198In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)
Targets&IC50
BAD Ser99:0.41 μM
AliasAlpha-NPB
Chemical Properties
Molecular Weight524.48
FormulaC29H31Cl2N3O2
Cas No.2247491-97-8
SmilesOc1ccccc1C(N1CCN(CC1)c1cccc(Cl)c1Cl)c1cccc(c1)C(=O)NC1CCCC1
Relative Density.1.35 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (85.8 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9067 mL9.5333 mL19.0665 mL95.3325 mL
5 mM0.3813 mL1.9067 mL3.8133 mL19.0665 mL
10 mM0.1907 mL0.9533 mL1.9067 mL9.5333 mL
20 mM0.0953 mL0.4767 mL0.9533 mL4.7666 mL
50 mM0.0381 mL0.1907 mL0.3813 mL1.9067 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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