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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $347 | 8-10 weeks | |
25 mg | $1,140 | 8-10 weeks | |
50 mg | $1,490 | 8-10 weeks | |
100 mg | $1,990 | 8-10 weeks | |
1 mL x 10 mM (in DMSO) | $382 | 8-10 weeks |
Description | NU6300 is an inhibitor of the first covalent ATP-competitive CDK2. |
In vitro | NU6300 blocks the inhibitor binding site. The effect was time-dependent and relatively slow, with less than 50% reduction of the apparent binding capacity in 20 hr. NU6300 is a covalent CDK2 inhibitor that illustrates the potential of using vinyl sulfones to mediate irreversible inhibition. |
Molecular Weight | 413.49 |
Formula | C20H23N5O3S |
Cas No. | 2070015-09-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 32 mg/mL (77.39 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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