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Ocrelizumab
Catalog No. T77482
Alias IDC-2403, IDC2403
Ocrelizumab (IDC-2403) is a humanized monoclonal antibody directed against CD20 for the treatment of multiple sclerosis.
Ocrelizumab
Ocrelizumab
Catalog No. T77482Alias IDC-2403, IDC2403
Ocrelizumab (IDC-2403) is a humanized monoclonal antibody directed against CD20 for the treatment of multiple sclerosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $245 | In Stock | |
| 5 mg | $647 | In Stock | |
| 10 mg | $1,038 | In Stock | |
| 25 mg | $1,765 | In Stock | |
| 50 mg | $2,650 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ocrelizumab (IDC-2403) is a humanized monoclonal antibody directed against CD20 for the treatment of multiple sclerosis. |
| In vivo | In a mouse model of multiple sclerosis, Ocrelizumab, administered subcutaneously or intravenously at a dose of 7.5 mg/kg once daily for 18 days, induced B-cell depletion by an antibody-dependent cellular cytotoxicity (ADCC) mechanism to inhibit lesions. In C57BL/6 mice, Ocrelizumab administered intravenously at a dose of 50 μg on days 7, 14, and 21 significantly reduced B and T cells in the blood, lymph nodes, and spleen.[1][2] |
| Alias | IDC-2403, IDC2403 |
| Molecular Weight | 145.5 kDa |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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