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Pacmilimab
🥰Excellent
Catalog No. T77128Cas No. 2145091-51-4
Alias CX-072, CX072
Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.
Pacmilimab
Pacmilimab
🥰Excellent
Purity: 95%
Catalog No. T77128Alias CX-072, CX072Cas No. 2145091-51-4
Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $169 | In Stock | |
| 5 mg | $448 | In Stock | |
| 10 mg | $715 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,460 | In Stock |
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Concentration:6.96 mg/mL
Purity:95%
Contact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors. |
| In vivo | Pacmilimab demonstrated anti-tumor effects in MC38 tumor model mice that matched the effects of the parental antibody at the same dose. [1] Pacmilimab predominantly clustered in tumor tissues of PD-L1-expressing mice, with minimal uptake in peripheral non-tumorigenic lymphoid tissues. This distributional property suggests that its uptake in non-tumorigenic PD-L1-expressing tissues is limited and may contribute to the maintenance of immune self-tolerance. [1] |
| Alias | CX-072, CX072 |
| Cas No. | 2145091-51-4 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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