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PAz-PC
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Catalog No. T35956Cas No. 117746-89-1
Alias PAzePC, Azelaoyl PC, 1-Palmitoyl-2-Azelaoyl PC
PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption induced by heat-inactivated Staphylococcus aureus (HKSA).
PAz-PC
😃Good
Catalog No. T35956Alias PAzePC, Azelaoyl PC, 1-Palmitoyl-2-Azelaoyl PCCas No. 117746-89-1
PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption induced by heat-inactivated Staphylococcus aureus (HKSA).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | Inquiry | 35 days | |
| 5 mg | Inquiry | 35 days | |
| 10 mg | Inquiry | 35 days | |
| 25 mg | Inquiry | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption induced by heat-inactivated Staphylococcus aureus (HKSA). |
| In vitro | PAz-PC can cause acute lung endothelial cell barrier breakdown. [1] The oxidation of phospholipid PAz-PC can promote the permeability of Bax to mitochondrial membrane. [2] |
| Alias | PAzePC, Azelaoyl PC, 1-Palmitoyl-2-Azelaoyl PC |
| Molecular Weight | 665.84 |
| Formula | C33H64NO10P |
| Cas No. | 117746-89-1 |
| Smiles | [C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCC(O)=O)=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | PBS (pH 7.2): 1 mg/mL (1.5 mM), Sonication is recommended. DMF: 1 mg/mL (1.5 mM), Sonication is recommended. DMSO: 1 mg/mL (1.5 mM), Sonication is recommended. Ethanol: 8 mg/mL (12.01 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
PBS (pH 7.2)/DMF/DMSO/Ethanol
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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