Shopping Cart
- Remove All
Your shopping cart is currently empty
Poly-D-lysine hydrobromide (MW 30000-70000)
Catalog No. T40363Cas No. 27964-99-4
Alias Poly-D-lysine HBr (MW 30000-70000)
Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is an oral peptide CaSR agonist that eliminates proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.
Poly-D-lysine hydrobromide (MW 30000-70000)
Catalog No. T40363Alias Poly-D-lysine HBr (MW 30000-70000)Cas No. 27964-99-4
Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is an oral peptide CaSR agonist that eliminates proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | In Stock | |
| 10 mg | $48 | In Stock | |
| 25 mg | $98 | In Stock | |
| 50 mg | $156 | In Stock | |
| 100 mg | $228 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Poly-D-lysine hydrobromide (MW 30000-70000)"
Strontium chloride
T2340110476-85-4
Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.
- $50
Size
QTY
Evocalcet
KHK7580
T15261870964-67-3
Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).
- $33
Size
QTY
Cinacalcet hydrochloride
Cinacalcet HCl, Cinacalcet, AMG-073 hydrochloride, AMG-073 HCl
T2406364782-34-3
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and calcimimetic agent that enhances the sensitivity of parathyroid gland calcium-sensing receptors to serum calcium, thereby reducing parathyroid hormone secretion and decreasing serum calcium in the treatment of parathyroid diseases.
- $43
Size
QTY
Cinacalcet
AMG 073
T8403226256-56-0
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist used in the treatment of cardiovascular disease.
- $43
Size
QTY
Gadolinium chloride
Cited
T2279510138-52-0
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist
- $41
Size
QTY
CitedStrontium ranelate
S12911, Distrontium renelate
T1641135459-87-9
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in the treatment of severe osteoporosis.
- $32
Size
QTY
Tecalcet Hydrochloride
R-568 hydrochloride, R-568 (hydrochloride)
T13918177172-49-5In house
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.
- $30
Size
QTY
Calindol hydrochloride
T21758729610-18-8In house
Calindol hydrochloride is a potent orthosteric modulator (EC50: 132 nM) of the putative calcium-calcium-sensitive receptor (CaSR), inhibits Pi-induced VC, and delays the progression of calcification in vascular smooth muscle cells.
- $44
Size
QTY
AC265347
AC-265347
T295411253901-26-6
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to study neuroblastoma.
- $32
Size
QTY
Select Batch
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is an oral peptide CaSR agonist that eliminates proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells. |
| In vitro | In rabbits, Poly-D-lysine (PDL) elicits an immune response exclusively at low dosages. The concentration of Poly-D-lysine required to reduce PrPres levels by 50% is approximately 0.8 μg/mL or 50 nM. |
| Alias | Poly-D-lysine HBr (MW 30000-70000) |
| Formula | (C6H14N2O2)x.xHBr |
| Cas No. | 27964-99-4 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O: 30 mg/mL, Sonication is recommended. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Poly-D-lysine hydrobromide (MW 30000-70000) | purchase Poly-D-lysine hydrobromide (MW 30000-70000) | Poly-D-lysine hydrobromide (MW 30000-70000) cost | order Poly-D-lysine hydrobromide (MW 30000-70000) | Poly-D-lysine hydrobromide (MW 30000-70000) chemical structure | Poly-D-lysine hydrobromide (MW 30000-70000) in vitro | Poly-D-lysine hydrobromide (MW 30000-70000) formula
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.