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Calindol hydrochloride

Calindol hydrochloride
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Calindol hydrochloride

Catalog No. T21758Cas No. 729610-18-8
Calindol hydrochloride is a potent orthosteric modulator (EC50: 132 nM) of the putative calcium-calcium-sensitive receptor (CaSR), inhibits Pi-induced VC, and delays the progression of calcification in vascular smooth muscle cells.
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Pack SizePriceAvailabilityQuantity
1 mg$63In Stock
5 mg$152In Stock
10 mg$259In Stock
25 mg$546In Stock
50 mg$868In Stock
100 mg$1,390In Stock
500 mg$2,780In Stock
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Product Introduction

Bioactivity
Description
Calindol hydrochloride is a potent orthosteric modulator (EC50: 132 nM) of the putative calcium-calcium-sensitive receptor (CaSR), inhibits Pi-induced VC, and delays the progression of calcification in vascular smooth muscle cells.
Chemical Properties
Molecular Weight336.86
FormulaC21H21ClN2
Cas No.729610-18-8
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 80 mg/mL (237.49 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9686 mL14.8430 mL29.6859 mL148.4296 mL
5 mM0.5937 mL2.9686 mL5.9372 mL29.6859 mL
10 mM0.2969 mL1.4843 mL2.9686 mL14.8430 mL
20 mM0.1484 mL0.7421 mL1.4843 mL7.4215 mL
50 mM0.0594 mL0.2969 mL0.5937 mL2.9686 mL
100 mM0.0297 mL0.1484 mL0.2969 mL1.4843 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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