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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Propargyl-PEG3-amine is a PEG-based linker for PROTACs, connecting two essential ligands critical for PROTAC molecule formation. This linker facilitates selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the intended protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 187.24 |
Formula | C9H17NO3 |
Cas No. | 932741-19-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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