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PROTAC ER Degrader-4
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Catalog No. T13839Cas No. 2361114-15-8
PROTAC ER Degrader-4 is a PROTAC degrader of the estrogen receptor (ER) with an IC50 of 0.8 nM.
PROTAC ER Degrader-4
😃Good
Catalog No. T13839Cas No. 2361114-15-8
PROTAC ER Degrader-4 is a PROTAC degrader of the estrogen receptor (ER) with an IC50 of 0.8 nM.
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Product Introduction
Bioactivity
Chemical Properties
| Description | PROTAC ER Degrader-4 is a PROTAC degrader of the estrogen receptor (ER) with an IC50 of 0.8 nM. |
| In vitro | In the MCF-7 ER degradation cellular assay,PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM [1]. |
| Molecular Weight | 1005.2 |
| Formula | C53H67F3N6O8S |
| Cas No. | 2361114-15-8 |
| Relative Density. | 1.254 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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