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PS-166276

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Catalog No. T201008Cas No. 348089-57-6

PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of 28 nM against p38 kinase and an IC50 of 170 nM in the THP-1 TNFα assay.

PS-166276

PS-166276

😃Good
Catalog No. T201008Cas No. 348089-57-6
PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of 28 nM against p38 kinase and an IC50 of 170 nM in the THP-1 TNFα assay.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of 28 nM against p38 kinase and an IC50 of 170 nM in the THP-1 TNFα assay.
In vivo
PS166276, administered subcutaneously at a dose of 30 mg/kg in mice, inhibits the production of TNFα induced by LPS.
Chemical Properties
Molecular Weight398.51
FormulaC20H30N8O
Cas No.348089-57-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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