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RNase L-IN-2

🥰Excellent
Catalog No. T8591Cas No. 357618-26-9
Alias 5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one

RNase L-IN-2 is an activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.

RNase L-IN-2

RNase L-IN-2

🥰Excellent
Purity: 98.81%
Catalog No. T8591Alias 5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-oneCas No. 357618-26-9
RNase L-IN-2 is an activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.
Pack SizePriceAvailabilityQuantity
1 mg$133In Stock
2 mg$198In Stock
5 mg$298In Stock
10 mg$453In Stock
25 mg$747In Stock
50 mg$1,050In Stock
100 mg$1,420In Stock
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Purity:98.81%
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Product Introduction

Bioactivity
Description
RNase L-IN-2 is an activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.
Alias5-(3-hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one
Chemical Properties
Molecular Weight298.36
FormulaC16H14N2O2S
Cas No.357618-26-9
SmilesO=C1N=C(C2=CC(O)=CC=C2)NC3=C1C(CCCC4)=C4S3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 2.98 mg/mL (10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3517 mL16.7583 mL33.5166 mL167.5828 mL
5 mM0.6703 mL3.3517 mL6.7033 mL33.5166 mL
10 mM0.3352 mL1.6758 mL3.3517 mL16.7583 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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