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Shz 1

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Purity:99.79%

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COA HPLC HNMR

Shz 1

Catalog No. T23351Cas No. 326886-05-9

Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.

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Pack Size	Price	Availability
1 mg	$33	In Stock
5 mg	$80	In Stock
10 mg	$128	In Stock
25 mg	$289	In Stock
50 mg	$455	In Stock
100 mg	$672	In Stock
500 mg	$1,430	In Stock
1 mL x 10 mM (in DMSO)	$89	In Stock

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Related Compound Libraries of "Shz 1"

Product Introduction

Bioactivity

Description	induces phenotypic differentiation
In vitro	Shz-1 showes a ~1.5-fold increase in cardiac transcripts of the Nkx2.5 gene. Shz-1 augments the expression of transcripts of the total sarcomeric TPM1 (both TPM1α & TPM1κ) and sarcomeric TPM4α. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].

Chemical Properties

Molecular Weight	355.21
Formula	C13H11BrN2O3S
Cas No.	326886-05-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 4.8 mg/mL (13.51 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8152 mL	14.0762 mL	28.1524 mL	140.7618 mL
5 mM	0.5630 mL	2.8152 mL	5.6305 mL	28.1524 mL
10 mM	0.2815 mL	1.4076 mL	2.8152 mL	14.0762 mL

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In Vivo Formulation Calculator (Clear solution)

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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