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SJ572403 is an inhibitor of disordered protein p27 with Kd of 2.2 mM for specific regions within the D2 subdomain of p27-KID. SJ572403 can be used in studies about diseases with intrinsically disordered proteins.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $35 | In Stock | |
5 mg | $83 | In Stock | |
10 mg | $128 | In Stock | |
25 mg | $257 | In Stock | |
50 mg | $413 | In Stock | |
100 mg | $597 | In Stock | |
200 mg | $788 | In Stock | |
1 mL x 10 mM (in DMSO) | $92 | In Stock |
Description | SJ572403 is an inhibitor of disordered protein p27 with Kd of 2.2 mM for specific regions within the D2 subdomain of p27-KID. SJ572403 can be used in studies about diseases with intrinsically disordered proteins. |
In vitro | SJ572403 (10 μM-3 mM) replaces p27-D2 on Cdk2/cyclin A and partially restores Cdk2 kinase activity. SJ572403 (0-3 mM) modulates Cdk regulation of p27[1]. |
Alias | SJ403 |
Molecular Weight | 275.31 |
Formula | C13H17N5O2 |
Cas No. | 19970-45-7 |
Smiles | CCn1c(C)c(C)n2c1nc1n(C)c(=O)n(C)c(=O)c21 |
Relative Density. | 1.41 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 12.5 mg/mL (45.4 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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