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SR31527
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Catalog No. T28848Cas No. 311814-78-5
Alias SR31527 chloride, SR-31527, SR 31527
SR31527 (SR31527 chloride) is a potent KIFC1 inhibitor with an IC50 of 6.6 µM against KIFC1. SR31527 chloride has a moderate inhibitory effect on cell viability and colony formation.
SR31527
😃Good
Catalog No. T28848Alias SR31527 chloride, SR-31527, SR 31527Cas No. 311814-78-5
SR31527 (SR31527 chloride) is a potent KIFC1 inhibitor with an IC50 of 6.6 µM against KIFC1. SR31527 chloride has a moderate inhibitory effect on cell viability and colony formation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,350 | 6-8 weeks | |
| 50 mg | $1,760 | 6-8 weeks | |
| 100 mg | $2,720 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | SR31527 (SR31527 chloride) is a potent KIFC1 inhibitor with an IC50 of 6.6 µM against KIFC1. SR31527 chloride has a moderate inhibitory effect on cell viability and colony formation. |
| Targets&IC50 | KIFC1:6.6 µM, KIFC1:25.4 nM(Kd) |
| In vitro | SR31527 (50 µ M ; 24h) induced the formation of multiple Spindle apparatus in MDA-MB-231, BT549 and MDA-MB-435s cells.[1] SR31527 (0-100 µ M ; 96 hours, 10-12 days) reduces the cell viability and colony formation of breast cancer cells, and is less cytotoxic to LL47 cells.[1] |
| Alias | SR31527 chloride, SR-31527, SR 31527 |
| Molecular Weight | 319.81 |
| Formula | C15H14ClN3OS |
| Cas No. | 311814-78-5 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.2 mg/mL (10 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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