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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $735 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,546 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,780 | In Stock |
Description | AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC). |
Targets&IC50 | EG5:2 nM |
Alias | AZD4877 |
Molecular Weight | 503.66 |
Formula | C28H33N5O2S |
Cas No. | 758722-49-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (109.2 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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