Shopping Cart
- Remove All
Your shopping cart is currently empty
Tauro-β-muricholic acid sodium
😃Good
Catalog No. T13093Cas No. 145022-92-0
Alias T-βMCA sodium
Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM).
Tauro-β-muricholic acid sodium
😃Good
Catalog No. T13093Alias T-βMCA sodiumCas No. 145022-92-0
Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 μg | 171 € | 35 days | |
| 1 mg | 321 € | 35 days | |
| 5 mg | 1.007 € | 35 days |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Tauro-β-muricholic acid sodium"
Forskolin
Cited
FSK, Colforsin, Coleonol
T293966575-29-9
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the heart, and has platelet anticoagulant and antihypertensive effects.
- 34 €
Size
QTY
CitedObeticholic Acid
INT-747, 6-Ethylchenodeoxycholic acid, 6-ECDCA
T1789459789-99-2
Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist with an EC50 of 99 nM and is able to upregulate IκB-α, KLF-2, and KLF-4 expression. Obeticholic Acid (6-ECDCA, INT-747) also shows potential for treating hepatic steatosis, inflammation, and fibrosis while increasing insulin sensitivity.
- 38 €
Size
QTY
Sevelamer hydrochloride
Sevelamer HCl
T6344152751-57-0
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
- 28 €
Size
QTY
Lithocholic acid Cited
3α-Hydroxy-5β-cholanic acid
T2202434-13-9
Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.
- 43 €
Size
QTY
CitedUrsodeoxycholic acid sodium
Ursodiol sodium, Ursodeoxycholic Acid (sodium salt), Ursodeoxycholate sodium, UDCA sodium, UDCA Na, Sodium Ursodeoxycholate
T290782898-95-5In house
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors,
- 28 €
Size
QTY
T0901317 Cited
T6690293754-55-9
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
- 30 €
Size
QTY
CitedGW 4064 Cited
T2233278779-30-9
GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).
- 43 €
Size
QTY
CitedHyodeoxycholic acid Cited
α-Hyodeoxycholic Acid, NSC 60672, HDCA
T296883-49-8
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
- 36 €
Size
QTY
CitedGSK2324
GSK-2324, GSK 2324
T274601020567-30-9In house
GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.
- 324 €
Size
QTY
Altenusin
T889531186-12-6In house
Altenusin is a natural nonsteroidal fungal metabolite, as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 μM.
- 369 €
Size
QTY
Chenodeoxycholic acid Cited
Chenodiol, CDCA
T0847474-25-9
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
- 52 €
Size
QTY
CitedDY268
DY-268, DY 268
T315871609564-75-1
DY268 is a compound based on trisubstituted pyrazolamide without any FXR agonist activity and cytotoxicity and can be used as an effective FXR antagonist (IC50 = 7.5 nM).
- 32 €
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM). |
| Targets&IC50 | FXR:40 μM |
| Alias | T-βMCA sodium |
| Molecular Weight | 537.69 |
| Formula | C26H44NNaO7S |
| Cas No. | 145022-92-0 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Tauro-β-muricholic acid sodium | purchase Tauro-β-muricholic acid sodium | Tauro-β-muricholic acid sodium cost | order Tauro-β-muricholic acid sodium | Tauro-β-muricholic acid sodium chemical structure | Tauro-β-muricholic acid sodium formula | Tauro-β-muricholic acid sodium molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.