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Hyodeoxycholic acid

Catalog No. T2968Cas No. 83-49-8
Alias α-Hyodeoxycholic Acid, NSC 60672, HDCA

Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.

Hyodeoxycholic acid

Hyodeoxycholic acid

Purity: 97.26%
Catalog No. T2968Alias α-Hyodeoxycholic Acid, NSC 60672, HDCACas No. 83-49-8
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
Pack SizePriceAvailabilityQuantity
50 mg$38In Stock
100 mg$53In Stock
1 mL x 10 mM (in DMSO)$57In Stock
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Purity:97.26%
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Product Introduction

Bioactivity
Description
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
Targets&IC50
TGR5/GPCR19:31.6 µM(EC50)
Aliasα-Hyodeoxycholic Acid, NSC 60672, HDCA
Chemical Properties
Molecular Weight392.57
FormulaC24H40O4
Cas No.83-49-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (127.37 mM), Sonication is recommended.
Ethanol: 72 mg/mL (183.4 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.5473 mL12.7366 mL25.4732 mL127.3658 mL
5 mM0.5095 mL2.5473 mL5.0946 mL25.4732 mL
10 mM0.2547 mL1.2737 mL2.5473 mL12.7366 mL
20 mM0.1274 mL0.6368 mL1.2737 mL6.3683 mL
50 mM0.0509 mL0.2547 mL0.5095 mL2.5473 mL
100 mM0.0255 mL0.1274 mL0.2547 mL1.2737 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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