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Timegadine hydrochloride
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Catalog No. T203602Cas No. 71080-06-3
Alias SR1368 hydrochloride
Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.
Timegadine hydrochloride
😃Good
Catalog No. T203602Alias SR1368 hydrochlorideCas No. 71080-06-3
Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity. |
| Alias | SR1368 hydrochloride |
| Molecular Weight | 401.96 |
| Formula | C20H24ClN5S |
| Cas No. | 71080-06-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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