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Trequinsin hydrochloride (HL 725) is a potent phosphodiesterase (PDE) inhibitor and inhibitor of platelet aggregation, and is a novel antihypertensive vasodilator for the study of cardiovascular disease.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $108 | In Stock | |
25 mg | $632 | 6-8 weeks | |
50 mg | $822 | 6-8 weeks | |
100 mg | $1,360 | 6-8 weeks |
Description | Trequinsin hydrochloride (HL 725) is a potent phosphodiesterase (PDE) inhibitor and inhibitor of platelet aggregation, and is a novel antihypertensive vasodilator for the study of cardiovascular disease. |
Targets&IC50 | platelet cAMP phosphodiesterase (PDE):0.25 nM |
In vitro | In addition to its cardioprotective and antihypertensive effects, Trequinsin hydrochloride exhibits significant antiplatelet activity.Trequinsin hydrochloride is a potent inhibitor of platelet cAMP phosphodiesterase (PDE) with an IC50 of 0.25 nM. [1] In addition, Trequinsin hydrochloride is a potent calcium agonist. [3] |
Alias | HL 725 |
Molecular Weight | 441.95 |
Formula | C24H28ClN3O3 |
Cas No. | 78416-81-6 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 40 mg/mL (90.51 mM), Sonication is recommended. DMSO: 50 mg/mL (113.13 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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