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Veltuzumab

🥰Excellent
Catalog No. T76765Cas No. 728917-18-8
Alias IMMU-106, IMMU106, hA20

Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that displays anti-proliferative, apoptotic, and antibody-dependent cytotoxic effects in vitro and inhibits tumor growth in mice harboring human lymphomas, and is indicated for use in non-Hodgkin's lymphoma (NHL).

Veltuzumab

Veltuzumab

🥰Excellent
Purity: 95%
Catalog No. T76765Alias IMMU-106, IMMU106, hA20Cas No. 728917-18-8
Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that displays anti-proliferative, apoptotic, and antibody-dependent cytotoxic effects in vitro and inhibits tumor growth in mice harboring human lymphomas, and is indicated for use in non-Hodgkin's lymphoma (NHL).
Pack SizePriceAvailabilityQuantity
1 mg$197In Stock
5 mg$463In Stock
10 mg$742In Stock
25 mg$1,120In Stock
50 mg$1,490In Stock
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Concentration:7.81 mg/mL
Purity:95%
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Product Introduction

Bioactivity
Description
Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that displays anti-proliferative, apoptotic, and antibody-dependent cytotoxic effects in vitro and inhibits tumor growth in mice harboring human lymphomas, and is indicated for use in non-Hodgkin's lymphoma (NHL).
Targets&IC50
Daudi cell lines:0.08-0.09 μg/mL (EC50)
In vitro
Veltuzumab was effective in reducing dissociation rates in human lymphoma cell lines and enhancing complement-dependent cytotoxicity in 1 of 3 cell lines, but did not exhibit other significant in vitro differences. [1]
Veltuzumab (0.001-10 μg/mL, 3 hours) had low EC50 values ranging from 0.08-0.09 μg/mL in Daudi cell lines. [1]
In vivo
Veltuzumab (intravenous or subcutaneous; 5, 20, and 60 μg; single dose) achieves control of tumor growth, or removal of circulating and adherent B cells, at low doses in mouse models. [1]
Veltuzumab (intraperitoneal; 0.05-35 μg) demonstrated significant efficacy in in vivo studies. [1]
AliasIMMU-106, IMMU106, hA20
Chemical Properties
Cas No.728917-18-8
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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