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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (IC50) of 0.96 nM for the wild-type EGFR and 0.67 nM for the L858R mutant variant. This compound has been shown to induce G0/G1 cell cycle arrest and apoptosis in targeted cells [1]. |
Molecular Weight | 494.58 |
Formula | C30H30N4O3 |
Cas No. | 2470908-90-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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