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YTK-105

Name: YTK-105
Brand: TargetMol
SKU: T87944
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T87944Cas No. 774192-20-0

Alias YTK105, YTK 105

YTK-105 is a ligand targeting autophagy that binds to p62.

YTK-105

🥰Excellent

Catalog No. T87944Alias YTK105, YTK 105Cas No. 774192-20-0

YTK-105 is a ligand targeting autophagy that binds to p62.

Pack Size	Price	Availability
5 mg	$74	In Stock
10 mg	$116	In Stock
25 mg	$232	In Stock
50 mg	$380	In Stock
100 mg	$600	In Stock

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COA HNMR

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	YTK-105 is a ligand targeting autophagy that binds to p62.
In vitro	YTK-105 is a ligand for the p62-ZZ structural domain that activates p62-dependent selective macroautophagy.YTK-105 can be used in the design of AUTOTAC.
Alias	YTK105, YTK 105

Chemical Properties

Molecular Weight	257.33
Formula	C₁₆H₁₉NO₂
Cas No.	774192-20-0
Smiles	OCCNCC=1C=CC=C(OCC=2C=CC=CC2)C1
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | store at -20°C | Shipping with blue ice.

Solubility Information

DMSO: 150 mg/mL (582.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8861 mL	19.4303 mL	38.8606 mL	194.3030 mL
5 mM	0.7772 mL	3.8861 mL	7.7721 mL	38.8606 mL
10 mM	0.3886 mL	1.9430 mL	3.8861 mL	19.4303 mL
20 mM	0.1943 mL	0.9715 mL	1.9430 mL	9.7152 mL
50 mM	0.0777 mL	0.3886 mL	0.7772 mL	3.8861 mL
100 mM	0.0389 mL	0.1943 mL	0.3886 mL	1.9430 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc