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Description | Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. |
In vitro | In vitro, Zabofloxacin shows a highly potent activity against clinical isolates of penicillin-sensitive S. pneumoniae (minimum inhibitory concentration with MIC90 of 0.03 mg/L) and penicillin-resistant S. pneumoniae (MIC90: 0.03 mg/L). Against quinolone-resistant S. pneumoniae, zabofloxacin (MIC90: 1 mg/L) is more active than ciprofloxacin, sparfloxacin, and moxifloxacin. |
Alias | DW-224a |
Molecular Weight | 437.86 |
Formula | C19H21ClFN5O4 |
Cas No. | 623574-00-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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