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ZK53

Name: ZK53
Brand: TargetMol
SKU: T80725
Price: 66 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T80725Cas No. 3031789-26-8

ZK53 is a selective and potent activator of mitochondrial casein hydrolase protease P (HsClpP).ZK53 induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.ZK53 inhibits tumour growth in xenografts and native mouse models.

ZK53

🥰Excellent

Purity: 99.36%

Catalog No. T80725Cas No. 3031789-26-8

Pack Size	Price	Availability
1 mg	$66	In Stock
5 mg	$159	In Stock
10 mg	$238	In Stock
25 mg	$397	In Stock
50 mg	$588	In Stock
100 mg	$788	In Stock
500 mg	$1,690	In Stock

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Related Compound Libraries of "ZK53"

Bioactive Compound Library

L400017760 compounds

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Fluorochemical Library

L51002684 compounds

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Apoptosis Compound Library

L90002394 compounds

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Bioactive Compounds Library Max

L401026342 compounds

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Purity:99.36%

Resource Download

COA HNMR HPLC

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	424.28
Formula	C₁₉H₂₀BrF₂N₃O
Cas No.	3031789-26-8
Smiles	O=C(NCC1=CC=C(Br)C=C1)N(CC2)CCN2CC3=CC(F)=CC(F)=C3
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (188.55 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3569 mL	11.7847 mL	23.5693 mL	117.8467 mL
5 mM	0.4714 mL	2.3569 mL	4.7139 mL	23.5693 mL
10 mM	0.2357 mL	1.1785 mL	2.3569 mL	11.7847 mL
20 mM	0.1178 mL	0.5892 mL	1.1785 mL	5.8923 mL
50 mM	0.0471 mL	0.2357 mL	0.4714 mL	2.3569 mL
100 mM	0.0236 mL	0.1178 mL	0.2357 mL	1.1785 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

HsClpP