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CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled

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CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled

Catalog No. TMPK-00078

CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and the accession number is P32970-1.

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Pack Size	Price	Availability
100 μg	$1,400	7-10 days
500 μg	$3,720	7-10 days
1 mg	$6,210	7-10 days

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Biological Description

Description	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and the accession number is P32970-1.
Species	Human
Expression System	HEK293 Cells
Tag	N-His
Accession Number	P32970-1
Synonyms	TNFSF7, Ki-24 antigen,CD70,TNFSF7G,CD70 molecule,CD27 Ligand,CD27-L,CD27LG
Construction	Leu50-Pro193
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	51.8 kDa (predicted). Due to glycosylation, the protein migrates to 63-68 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

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Keywords

Ki-24 antigen CD-70 TNFSF-7 TNFSF 7 CD 70