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LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)

LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)
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LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-04781
LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.9 kDa and the accession number is D9IDM8.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
50 μg$228In Stock
100 μg$4057-10 days
200 μg$7167-10 days
500 μg$1,5207-10 days
Bulk & Custom
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Biological Description

Biological Information
Testing in progress
Description
LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.9 kDa and the accession number is D9IDM8.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberD9IDM8
Synonyms
ILT-2,LIR-1,CD85j,LIR1,MIR7,leukocyte immunoglobulin like receptor B1,ILT2,XXbac-BCX85G21.4,MIR-7
Construction
The Human LILRB1 (ADJ55949.1) (Met1-His458) was expressed with the Fc region of Human IgG1 at the C-terminus.
Protein Purity
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc)
Molecular Weight73.9 kDa (predicted)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords