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(+)-Coclaurine

Name: (+)-Coclaurine
Brand: TargetMol
SKU: T5766
Price: 32 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T5766Cas No. 2196-60-3

Alias Coclaurine

(+)-Coclaurine is a natural product.

(+)-Coclaurine

😃Good

Catalog No. T5766Alias CoclaurineCas No. 2196-60-3

(+)-Coclaurine is a natural product.

Pack Size	Price	Availability	Quantity
5 mg	458 €	Backorder

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Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	(+)-Coclaurine is a natural product.
In vivo	Coclaurine 25 ug produced an inhibition of locomotor activity, ptosis and catalepsy. One hour after injection it produced stereotyped behaviour,such as sniffing and gnawing.Pretreatment with coclaurine 25 ug suppressed locomotor activation and rotational behaviour induced by apomorphine and methamphetamine.
Alias	Coclaurine

Chemical Properties

Molecular Weight	285.34
Formula	C₁₇H₁₉NO₃
Cas No.	2196-60-3
Smiles	C([C@@H]1C=2C(=CC(OC)=C(O)C2)CCN1)C3=CC=C(O)C=C3
Relative Density.	1.232g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45 mg/mL (157.7 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5046 mL	17.5230 mL	35.0459 mL	175.2296 mL
5 mM	0.7009 mL	3.5046 mL	7.0092 mL	35.0459 mL
10 mM	0.3505 mL	1.7523 mL	3.5046 mL	17.5230 mL
20 mM	0.1752 mL	0.8761 mL	1.7523 mL	8.7615 mL
50 mM	0.0701 mL	0.3505 mL	0.7009 mL	3.5046 mL
100 mM	0.0350 mL	0.1752 mL	0.3505 mL	1.7523 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Inhibitorpostsynapticalkaloid(R)-Coclaurineinhibit(+)-CoclaurineBenzyltetrahydroisoquinoline(+) Coclaurined-Coclaurine(+)Coclaurine