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(±)11,12-DiHETE

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Catalog No. T37334Cas No. 867350-92-3

(±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11,12-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.

(±)11,12-DiHETE

(±)11,12-DiHETE

😃Good
Catalog No. T37334Cas No. 867350-92-3
(±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11,12-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.
Pack SizePriceAvailabilityQuantity
25 μg$263 35 days
50 μg$488 35 days
100 μg$923 35 days
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Product Introduction

Bioactivity
Description
(±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11,12-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.
Chemical Properties
Molecular Weight336.472
FormulaC20H32O4
Cas No.867350-92-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 30 mg/mL (89.16 mM), Sonication is recommended.
DMF: 30 mg/mL (89.16 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (1.49 mM), Sonication is recommended.
DMSO: 30 mg/mL (89.16 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/Ethanol/DMF/DMSO
1mg5mg10mg50mg
1 mM2.9720 mL14.8601 mL29.7202 mL148.6008 mL
Ethanol/DMF/DMSO
1mg5mg10mg50mg
5 mM0.5944 mL2.9720 mL5.9440 mL29.7202 mL
10 mM0.2972 mL1.4860 mL2.9720 mL14.8601 mL
20 mM0.1486 mL0.7430 mL1.4860 mL7.4300 mL
50 mM0.0594 mL0.2972 mL0.5944 mL2.9720 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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