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8(S),15(S)-DiHETE

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Catalog No. T37156Cas No. 80234-65-7

8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 μM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.

8(S),15(S)-DiHETE
Other Forms of 8(S),15(S)-DiHETE:

8(S),15(S)-DiHETE

😃Good
Catalog No. T37156Cas No. 80234-65-7
8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 μM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.
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25 μg$23835 days
50 μg$44835 days
100 μg$84335 days
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Product Introduction

Bioactivity
Description
8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 μM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.
Chemical Properties
Molecular Weight336.47
FormulaC20H32O4
Cas No.80234-65-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: >50 mg/mL (per Rao Maddipati)
DMSO: >50 mg/mL (per Rao Maddipati)
Ethanol: >50 mg/mL (per Rao Maddipati)
PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE)

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

8,15DiHETE8(S),15(S)DiHETE8(S),15(S) DiHETE
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