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5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $243 | 35 days | |
50 μg | $390 | 35 days | |
100 μg | $728 | 35 days |
Description | 5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM. |
Molecular Weight | 336.472 |
Formula | C20H32O4 |
Cas No. | 82200-87-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: >50 mg/mL (per Rao Maddipati) DMF: >50 mg/mL (per Rao Maddipati) Ethanol: >50 mg/mL (per Rao Maddipati) PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE) |
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