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5(S),6(R)-11-trans DiHETE

Name: 5(S),6(R)-11-trans DiHETE
Brand: TargetMol
SKU: T37651
Rating: 4.5 (1 reviews)

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Catalog No. T37651Cas No. 129263-59-8

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue. The isomerase activity responsible for the conversion of leukotriene B4 (LTB4) to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation. 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase. The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.

5(S),6(R)-11-trans DiHETE

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Catalog No. T37651Cas No. 129263-59-8

Pack Size	Price	Availability	Quantity
1 mg	$2,598	Backorder

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	336.47
Formula	C₂₀H₃₂O₄
Cas No.	129263-59-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Ethanol: 50.00 mg/mL (148.60 mM)

DMSO: 50.00 mg/mL (148.60 mM)

PBS (pH 7.2): 1.00 mg/mL (2.97 mM)

DMF: 50.00 mg/mL (148.60 mM)

Solution Preparation Table

PBS (pH 7.2)/Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.9720 mL	14.8602 mL	29.7203 mL	148.6017 mL

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5944 mL	2.9720 mL	5.9441 mL	29.7203 mL
10 mM	0.2972 mL	1.4860 mL	2.9720 mL	14.8602 mL
20 mM	0.1486 mL	0.7430 mL	1.4860 mL	7.4301 mL
50 mM	0.0594 mL	0.2972 mL	0.5944 mL	2.9720 mL
100 mM	0.0297 mL	0.1486 mL	0.2972 mL	1.4860 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5(S),6(R)11trans DiHETE5(S),6(R) 11 trans DiHETE5,611-trans DiHETE